Paul is contrasting human wisdom and wisdom that comes from God. Paul was highly educated and could have impressed everyone with everything he knew, but instead focused on Jesus. Human wisdom without Godly wisdom is a dangerous thing. That’s what the people who ordered Jesus’ death were like. Paul isn’t opposed to a good education, but spiritual wisdom is far more important.
Spiritual wisdom should always take priority over human wisdom in our decision-making. Human wisdom is self-centered; spiritual wisdom is God and others centered. Which one drives your reactions?