Mattityahu 19:4-5

But Rebbe, Melech HaMoshiach said in reply, Have you not read that HaBoreh (The Creator, Yotzer) bereshis (in the beginning) created them zachar (male) and nekevah (female)? And he said, Because of this, YAAZAV ISH ES AVIV VES IMMO VDAVAK BISHTO VHAYU LVASAR ECHAD (a man will leave his father and his mother and will be joined to his isha (wife), and the two will be one flesh).