Daniel 8:8-9

Then the male goat magnified himself exceedingly, and when he was [young and] strong, the great horn (Alexander) was [suddenly] broken; and in its place there came up four prominent horns [among whom the kingdom was divided, one] toward [each of] the four winds of heaven. Out of one of them (Antiochus IV Epiphanes) came forth a rather small horn [but one of irreverent presumption and profane pride] which grew exceedingly powerful toward the south, toward the east, and toward the Beautiful Land (Israel). [Dan 8:23]